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Education Resource Center

Your one stop shop for everything you need to know about Mask-Free NIV.

Clinical Research

Learn more about applications of Vapotherm technology through clinical studies and research.

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New Study Adds Evidence for Use of Vapotherm® High Velocity Therapy as First-Line Support on Severely Hypercapnic COPD Patients

Vapotherm high velocity therapy is an attractive alternative to traditional noninvasive positive pressure ventilation (NiPPV) for respiratory distress. This approach—which is a form of Mask-Free NIV®—redefines the notion that ventilatory support requires a mask-and-pressure-based mechanism of action. High velocity therapy, uses a primarily flush-based mechanism and a comfortable cannula interface to provide ventilatory support. Some

Keeping This Complex COVID-19 Patient Off the Vent —A Case Story of Inhaled Epoprostenol, High Velocity Therapy, and Healthcare Team Perseverance

Velocity – Ep 9 – Physicians discuss research on Mask-Free NIV for COPD patients

Hospital Case Studies

Norman Regional Health System

Norman Regional Health System streamlines clinician workflow with Vapotherm® Units

Putnam County Hospital

Putnam County Hospital saves money and improves patient experience with Vapotherm

Florida Hospital at Connerton

Florida Hospital at Connerton provides greater opportunities for patients and fewer invasive procedures with Vapotherm

Gaylord Hospital

Gaylord Hospital returns patients to the highest level of function with early mobilization using Vapotherm


A community hospital level II nursery reduces transports by over 80%

Madonna Rehabilitation Hospitals

Madonna Rehabilitation Hospitals improve patient outcomes with Vapotherm

Patient Case Studies

Use of High Velocity Therapy for Reversing Pneumothorax

By Marcos Cesar Ramos Mello, Hospital BP – A Beneficência Portuguesa de SP, Luciana Dalla Torres, Hospital BP – A Beneficência Portuguesa de SP, Alessandra Cristina Marques dos Santos, Hospital BP – A Beneficência Portuguesa de SP, Heloisa Maria Khader, Hospital BP – A Beneficência Portuguesa de SP, Juliana Pacheco, Hospital BP – A Beneficência

Helping Avoid Intubation in Complex COVID-19

apotherm’s high velocity therapy is a tool for treating respiratory distress.

COPD Exacerbation

Vapotherm resulted in rapid improvement that is believed to have averted the use of mechanical ventilation and ICU admission.

COPD Exacerbation (CAH)

Hi-VNI Technology helped provide adequate ventilatory support for an AECOPD patient.

CHF Crisis

Vapotherm provided a decrease in work of breathing over conventional oxygen therapy.

NiPPV Intolerance

A patient who demonstrated increased anxiety with NIPPV finds success with Vapotherm.

Rescue from NiPPV & HFNC Failure

HVNI rescued a patient in acute respiratory failure receiving HFNO therapy post-extubation.

Severe Bronchiolitis

HVNI used effectively in the management of severe bronchiolitis in a small child.