Case Studies

CAUTION: US Federal law restricts this device to sale by or on the order of a physician. Indications, contraindications, warnings, and instructions for use can be found in the product labelling supplied with each device or at For spontaneously breathing patients. High Velocity Therapy (HVT) does not provide total ventilatory requirements of the patient. It is not a ventilator. Decisions surrounding patient care depend on the physician’s professional judgment in consideration of all available information for the individual case, including escalation of care depending on patient condition. 


Norman Regional Health System streamlines clinician workflow with Vapotherm® Units

Putnam County Hospital saves money and improves patient experience with Vapotherm

Florida Hospital at Connerton provides greater opportunities for patients and fewer invasive procedures with Vapotherm

Gaylord Hospital returns patients to the highest level of function with early mobilization using Vapotherm

A community hospital level II nursery reduces transports by over 80%

Madonna Rehabilitation Hospitals improve patient outcomes with Vapotherm


NiPPV Rescue of COPD Patient with Vapotherm High Velocity Therapy

A 72-year-old male with a history of chronic obstructive pulmonary disease (COPD), hypertension and chronic atrial fibrillation presented to the Emergency Department (ED) at a Tertiary Medical Center in the northeastern region with shortness of breath.  His vital signs showed a blood pressure (BP) of 146/80 mmHg, a heart rate of 96 beats per minute, a respiratory rate (RR) of 28 breaths per minute, an oxygen saturation of 82%, and a temperature 101.6°F. Physical assessment revealed an irregularly irregular heart rhythm, breath sounds with bilateral air entry, but diminished, a soft, non-tender abdomen and pulses palpable in all extremities.

Use of High Velocity Therapy with Inline Nebulization in Avoiding Intubation and PICU admission in Status Asthmaticus complicated by a COVID-19 Infection

Asthma is the most common chronic disease in childhood. Acute asthma exacerbations are one of the most common reasons for presentation to the Emergency Department (ED) and for hospitalization in the pediatric age.

Use of High Velocity Nasal Insufflation in combination with servo controlled delivery

Ambulation, mobilization and training area crucial part within the management of severely dyspneic patients awaiting lung transplant.

Use of High Velocity Therapy for Reversing Pneumothorax

Pneumothorax, or the presence of air in the pleural cavity, is a frequent condition in clinical practice. The standards of conduct for the pneumothorax approach depends on the patient’s clinical conditions and the magnitude of pneumothorax.

Helping Avoid Intubation in Complex COVID-19

Vapotherm’s high velocity therapy is a tool for treating respiratory distress. Although individual results may vary, Vapotherm believes this case study is an example of the clinical benefit Vapotherm’s high velocity therapy can have on patient ambulation.

COPD Exacerbation

Vapotherm resulted in rapid improvement that is believed to have averted the use of mechanical ventilation and ICU admission.

COPD Exacerbation (CAH)

Hi-VNI Technology helped provide adequate ventilatory support for an AECOPD patient.

CHF Crisis

Vapotherm provided a decrease in work of breathing over conventional oxygen therapy.

NiPPV Intolerance

A patient who demonstrated increased anxiety with NIPPV finds success with Vapotherm.

Rescue from NiPPV & HFNC Failure

HVNI rescued a patient in acute respiratory failure receiving HFNO therapy post-extubation.

Severe Bronchiolitis

HVNI used effectively in the management of severe bronchiolitis in a small child.